🏈StatLine
Week 1Final
WinnerSF

San Francisco 49ers

(10-7)41
–
DET

Detroit Lions

(3-13-1)33
Sunday, September 12, 2021
5:00 PM UTC
Ford Field · Detroit, MI

Head-to-Head History

San Francisco 49ers vs Detroit Lions(2021-2024)

Series is tied

SF (1)2 games(1) DET
50%50%

Avg Points/Game

SF

37.5

vs

DET

36.5

Highest Score

SF

41

vs

DET

40

Lowest Score

SF

34

vs

DET

33

Current Streak

DET

1W

SF Home/Away

Home

0-1

Away

1-0

Biggest Win

SF

+8

2021 Week 1

Game History(2 games)
SeasonWeekDateSFScoreDET
2024Wk 17Dec 31, 2024H34-40A
2021Wk 1Sep 12, 2021A41-33H

Team Rosters

San Francisco 49ersAway
1WR
Deebo Samuel1,405 rec yds, 6 TD
2QB
Jimmy Garoppolo3,810 pass yds, 20 TD
3TE
George Kittle910 rec yds, 6 TD
4WR
Brandon Aiyuk826 rec yds, 5 TD
5RB
Elijah Mitchell963 rush yds, 5 TD
Detroit LionsHome
1WR
Amon-Ra St. Brown912 rec yds, 5 TD
2QB
Jared Goff3,245 pass yds, 19 TD
3RB
D'Andre Swift617 rush yds, 5 TD
4TE
T.J. Hockenson583 rec yds, 4 TD
5WR
Kalif Raymond576 rec yds, 4 TD