🏈StatLine
Week 7Final
WinnerIND

Indianapolis Colts

(9-8)30
–
SF

San Francisco 49ers

(10-7)18
Monday, October 25, 2021
12:20 AM UTC
Levi's Stadium · Santa Clara, CA

Head-to-Head History

Indianapolis Colts vs San Francisco 49ers(2021-2025)

Series is tied

IND (1)2 games(1) SF
50%50%

Avg Points/Game

IND

28.5

vs

SF

33.0

Highest Score

IND

30

vs

SF

48

Lowest Score

IND

27

vs

SF

18

Current Streak

SF

1W

IND Home/Away

Home

0-1

Away

1-0

Biggest Win

SF

+21

2025 Week 16

Game History(2 games)
SeasonWeekDateINDScoreSF
2025Wk 16Dec 23, 2025H27-48A
2021Wk 7Oct 25, 2021A30-18H

Team Rosters

Indianapolis ColtsAway
1RB
Jonathan Taylor1,811 rush yds, 18 TD
2QB
Carson Wentz3,563 pass yds, 27 TD
3WR
Michael Pittman Jr.1,082 rec yds, 6 TD
4RB
Nyheim Hines276 rush yds, 2 TD
5WR
Zach Pascal384 rec yds, 3 TD
San Francisco 49ersHome
1WR
Deebo Samuel1,405 rec yds, 6 TD
2QB
Jimmy Garoppolo3,810 pass yds, 20 TD
3TE
George Kittle910 rec yds, 6 TD
4WR
Brandon Aiyuk826 rec yds, 5 TD
5RB
Elijah Mitchell963 rush yds, 5 TD