🏈StatLine
Week 5Final
SF

San Francisco 49ers

(10-7)10
–
WinnerARI

Arizona Cardinals

(11-6)17
Sunday, October 10, 2021
8:25 PM UTC
State Farm Stadium · Glendale, AZ

Head-to-Head History

San Francisco 49ers vs Arizona Cardinals(2021-2025)

Arizona Cardinals leads the all-time series

SF (2)6 games(4) ARI
33%67%

Avg Points/Game

SF

21.8

vs

ARI

26.0

Highest Score

SF

41

vs

ARI

47

Lowest Score

SF

10

vs

ARI

15

Current Streak

SF

2W

SF Home/Away

Home

1-2

Away

1-2

Biggest Win

ARI

+23

2024 Week 18

Game History(6 games)
SeasonWeekDateSFScoreARI
2025Wk 11Nov 16, 2025A41-22H
2025Wk 3Sep 21, 2025H16-15A
2024Wk 18Jan 5, 2025A24-47H
2024Wk 5Oct 6, 2024H23-24A
2021Wk 9Nov 7, 2021H17-31A
2021Wk 5Oct 10, 2021A10-17H

Team Rosters

San Francisco 49ersAway
1WR
Deebo Samuel1,405 rec yds, 6 TD
2QB
Jimmy Garoppolo3,810 pass yds, 20 TD
3TE
George Kittle910 rec yds, 6 TD
4WR
Brandon Aiyuk826 rec yds, 5 TD
5RB
Elijah Mitchell963 rush yds, 5 TD
Arizona CardinalsHome
1QB
Kyler Murray3,787 pass yds, 24 TD
2RB
James Conner752 rush yds, 15 TD
3WR
Christian Kirk982 rec yds, 5 TD
4WR
A.J. Green848 rec yds, 3 TD
5WR
DeAndre Hopkins572 rec yds, 8 TD