🏈StatLine
Week 11Final
WinnerSF

San Francisco 49ers

(11-4)41
–
ARI

Arizona Cardinals

(3-12)22
Sunday, November 16, 2025
9:05 PM UTC
State Farm Stadium · Glendale, AZ

Head-to-Head History

San Francisco 49ers vs Arizona Cardinals(2020-2025)

Arizona Cardinals leads the all-time series

SF (3)8 games(5) ARI
38%63%

Avg Points/Game

SF

21.4

vs

ARI

24.0

Highest Score

SF

41

vs

ARI

47

Lowest Score

SF

10

vs

ARI

12

Current Streak

SF

2W

SF Home/Away

Home

1-3

Away

2-2

Biggest Win

ARI

+23

2024 Week 18

Game History(8 games)
SeasonWeekDateSFScoreARI
2025Wk 11Nov 16, 2025A41-22H
2025Wk 3Sep 21, 2025H16-15A
2024Wk 18Jan 5, 2025A24-47H
2024Wk 5Oct 6, 2024H23-24A
2021Wk 9Nov 7, 2021H17-31A
2021Wk 5Oct 10, 2021A10-17H
2020Wk 16Dec 26, 2020A20-12H
2020Wk 1Sep 13, 2020H20-24A

Team Rosters

San Francisco 49ersAway
1RB
Christian McCaffrey1,039 rush yds, 9 TD
2TE
George Kittle599 rec yds, 7 TD
3WR
Jauan Jennings566 rec yds, 8 TD
4QB
Brock Purdy1,737 pass yds, 17 TD
5QB
Mac Jones2,151 pass yds, 13 TD
Arizona CardinalsHome
1TE
Trey McBride1,098 rec yds, 10 TD
2QB
Jacoby Brissett2,911 pass yds, 19 TD
3WR
Michael Wilson818 rec yds, 5 TD
4WR
Marvin Harrison Jr.608 rec yds, 4 TD
5QB
Kyler Murray962 pass yds, 6 TD